What follows is a summary of production methods (culturing methods, specifically) for this coming season’s flu shots. In general, not much has changed beyond the viral formulation. All flu vaccines for this coming season are ethically produced, with essentially the same mix of avian cells (embryonated chicken eggs), insect cells (Sf9) and non-human mammalian cells (MDCK canine). We have summarized this information for all of the available and currently approved flu shots, although some of the flu shots deliver a viral formulation from prior years. Links to a number of FDA pages are provided – one for each of the vaccines and a link describing the 2022-2023 viral formulation.

Here’s the line-up:

Viral Formulation for 2022 – 2023:  Influenza Vaccines for the 2022-2023 Season | FDA

Approved Influenza Shots for 2022-2023 Season

Audenz – MDCK cells (non-human mammalian, canine).  Package Insert – AUDENZ (fda.gov)

Fluad Quadrivalent – Avian (embryonated chicken eggs).  Package Insert – FLUAD QUADRIVALENT (fda.gov)

Fluad – Avian (embryonated chicken eggs).  Package Insert – FLUAD (fda.gov)

Afluria Quadrivalent – Avian (embryonated chicken eggs).  Package Insert – AFLURIA QUADRIVALENT. (fda.gov)

Flucelvax Quadrivalent – MDCK cells (non-human mammalian, canine).  Package Insert – Flucelvax Quadrivalent (fda.gov)

Flulaval Quadrivalent – Avian (embryonated chicken eggs).  Package Insert – FluLaval Quadrivalent (fda.gov)

Afluria – Avian (embryonated chicken eggs).  Package Insert – Afluria (fda.gov)

Flulaval Trivalent – Avian (embryonated chicken eggs).  flulaval (fda.gov)

FluMist Trivalent and Quadrivalent – Avian (embryonated chicken eggs).  Package Insert – FluMist (fda.gov)

Fluarix Trivalent – Avian (embryonated chicken eggs).  FLUARIX (fda.gov)

Fluvirin Trivalent – Avian (embryonated chicken eggs).  Package Insert – Fluvirin (fda.gov)

AgriFlu Trivalent – Avian (embryonated chicken eggs).  Package Insert – AGRIFLU (fda.gov)

Fluzone, Fluzone High-Dose and Fluzone Intradermal Trivalent – Avian (embryonated chicken eggs).  271/371/372 Fluzone all presentations including High-Dose (fda.gov)

Flucelvax Trivalent – MDCK cells (non-human mammalian, canine).  download (fda.gov)

FluBlok Trivalent – Sf9 Insect cells.   Package Insert – Flublok (archive-it.org)

FluBlok Quadrivalent – Sf9 Insect cells.   Package Insert – Flublok Quadrivalent (fda.gov)

Fluarix Quadrivalent – Avian (embryonated chicken eggs).  Packaget Insert – FLUARIX QUADRIVALENT (fda.gov)

Fluzone Intradermal Quadrivalent and High Dose Quadrivalent – Avian (embryonated chicken eggs).  271/371/372 Fluzone all presentations including High-Dose (fda.gov)

Note:  Italics signify an approved influenza shot with a viral spectrum from prior years.  Click on the links for more details.