Study Shows Umbilical Cord Matrix New Rich Source of Stem Cells

MANHATTAN, Kan., January 17, 2003 (LifeSiteNews.com) – The cushioning material or matrix within the umbilical cord known as Wharton’s jelly is a rich and readily available source of primitive stem cells, according to findings by a research team at Kansas State University. The cells — called cord matrix stem cells to distinguish them from cord blood cells — can be obtained in a non-invasive manner from an abundant source of tissue that is typically discarded.

According to researchers Mark Weiss and Deryl Troyer, “Umbilical cord matrix cells could provide the scientific and medical research community with a non-controversial and easily attainable source of stem cells for developing treatments for Parkinson’s disease, stroke, spinal cord injuries, cancers and other conditions.”

Among the findings: Wharton’s jelly cells from pigs were propagated in the lab for more than a year without losing potency; they can be stored cryogenically and engineered to express foreign proteins.

The cells exhibit telomerase activity, a key indicator of stem cells, and they can be induced to form nerve cells, both neurons and glia, that produce a range of nerve-cell specific traits. Neurons are the nervous system cells that transmit signals; glial cells support the neurons.

On the basis of the encouraging results with animal tissue, the team broadened its investigations to human umbilical cord matrix cells with similar exciting findings — human umbilical cord matrix cells differentiate into neurons, too. The findings are published in the current edition of the journal Stem Cells.

See the study in the journal at:
http://stemcells.alphamedpress.org/cgi/content/abstract/21/1/50