Coriell Cell Repositories
Related Information on WI-38 Aborted Fetal Cell Line
Characterizations |
IDENTIFICATION OF SPECIES OF ORIGIN: |
Species of Origin Confirmed by Chromosome Analysis |
IDENTIFICATION OF SPECIES OF ORIGIN: |
Species of Origin Confirmed by Nucleoside Phosphorylase,Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis |
Publications
Guo WJ, Datta S, Band V, Dimri GP, Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins Molecular biology of the cell18:536-46 2006 |
PubMed ID: 17151361 |
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Von Kobbe C, May A, Grandori C, Bohr VA, Werner syndrome cells escape hydrogen peroxide-induced cell proliferation arrest. FASEB J18(15):1970-2 2004 |
PubMed ID: 15459124 |
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Skandalis A, Uribe E, A survey of splice variants of the human hypoxanthine phosphoribosyl transferase and DNA polymerase beta genes: products of alternative or aberrant splicing? Nucleic Acids Res32(22):6557-64 2004 |
PubMed ID: 15601998 |
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Hande MP, Balajee AS, Tchirkov A, Wynshaw-Boris A, Lansdorp PM, Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia. Hum Mol Genet10(5):519-28 2001 |
PubMed ID: 11181576 |
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Gyulai Z, Endresz V, Burian K, Pincus S, Toldy J, Cox WI, Meric C, Plotkin S, Gonczol E, Berencsi K, Cytotoxic T lymphocyte (CTL) responses to human cytomegalovirus pp65, IE1-Exon4, gB, pp150, and pp28 in healthy individuals: reevaluation of prevalence of IE1-specific CTLs. J Infect Dis181(5):1537-46 2000 |
PubMed ID: 10823751 |
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Piret B, Schoonbroodt S, Piette J, The ATM protein is required for sustained activation of NF-kappaB following DNA damage. Oncogene18(13):2261-71 1999 |
PubMed ID: 10327072 |
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Jongmans W, Vuillaume M, Chrzanowska K, Smeets D, Sperling K, Hall J, Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation. Mol Cell Biol17(9):5016-22 1997 |
PubMed ID: 9271379 |
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Duan C, Clemmons DR, Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression. J Biol Chem270:24844-51 1995 |
PubMed ID: 7559606 |
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Borsi L, Balza E, Gaggero B, Allemanni G, Zardi L, The alternative splicing pattern of the tenascin-C pre-mRNA is controlled by the extracellular pH. J Biol Chem270:6243-5 1995 |
PubMed ID: 7534307 |
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Futreal PA, Cochran C, Marks JR, Iglehart JD, Zimmerman W, Barrett JC, Wiseman RW, Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line. Cancer Res54:1791-4 1994 |
PubMed ID: 7511052 |
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Kilfeather SA, Collins D, McCormack P, Cotter T, O’Malley K, The effect of in vitro aging on human lung fibroblast beta-adrenergic receptor density, coupling and response. Mech Ageing Dev63:247-56 1992 |
PubMed ID: 1319530 |
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Jacobs, Characteristics of a human diploid cell designated MRC-5. Nature277:168 (1970):247-56 1970 |
PubMed ID: 1319530 |
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Futreal PA, Cochran C, Marks JR, Iglehart JD, Zimmerman W, Barrett JC, Wiseman RW, Cancer Res 54:1791-4 (1994) Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line.
PubMed ID: 7511052 |
Kilfeather SA, Collins D, McCormack P, Cotter T, O’Malley K, Mech Ageing Dev 63:247-56 (1992) The effect of in vitro aging on human lung fibroblast beta-adrenergic receptor density, coupling and response.
PubMed ID: 1319530 |
Jacobs, Nature 277:168 (1970), Characteristics of a human diploid cell designated MRC-5. |
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Thank you very much. I greatly appreciate your help and all the great work you do. God bless you all,…
Andrea, Paxlovid does not contain fetal cells. Aborted fetal cell lines were used in preclinical testing and were an essential…
I have Covid and my doctor has prescribed Paxlovid. I read that the development was compromised, but does the actual…
Chris, I sent a link to your email. You should have it shortly.
The link has disappeared. Where can I find the new updated ethical flu shot list for 2023-2024? Thank you.
Thank you kindly Jose for your help! Could you help me with one more …..Tamoxifen - for breast cancer? Does…
This is a reasonable rule of thumb, but there are exceptions. The poliomyelitis and rubella vaccines are examples of exceptions.…
Yvie, there is no comprehensive list, and this is due to the sheer number of approved drugs that are available.…
So, is it safe to say that if a medication is FDA approved before 1977 when fetal cell lines started…
Is there a list of medications that are abortion tainted? I'm in severe pain with fibromyalgia and am trying to…
Virginia, I have researched the development history of this drug and found no association with aborted fetal cell lines or…
Cefalexin was developed in 1967. This places its development prior to the advent of fetal cell lines in medical research.…
Do you have any information about the ethical status of Cephalexin (Keflex). If it is deemed unethical, then what is…
Is Aflibercept (Eylea) injection for Age related Macular Degeneration produced with or from human fetal cell lines?
Thank you, I came specifically looking for this information about nirsevimab.